In the XXI century, numerous States announced their plans to participate in the lunar race. The USA adopted the Artemis Program, China made public its Chinese Lunar Exploration Program with the participation of Russia and building together the International Lunar Research Station. All these programs are expected to include not only exploration purposes, but active use and utilization of the Moon and its orbits. However, the increase in lunar activities, as well as any activities, are suggested the creation of different physical debris (e.g., building materials, machinery, vehicles, general rubbish) plus chemical contaminants. Today problems with debris on the surface of the Earth and with space debris in the near-space have already been challenges for the whole of humanity. Therefore, the purpose of this paper will be to analyze different legal acts and mechanisms which can be used for the remediation of space debris on and around the Moon.